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Metformin inhibits endogenous NSCs ferroptosis in NSCs through AMPK activation To investigate the effects of metformin on ferroptosis of endogenous NSCs after SCI, we conducted relevant tests on rats 7 days post-injury

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442 The caged peptide-conjugated AIEgen probe (GCP) consisted of three parts: caged GO203 peptide, cathepsin B (CB) enzyme cleavable peptide, and PyTPA

However when gluathione stores are depleted this negative feedback is lost and there is increased production of - glutamyl cysteine in an attempt to replenish the glutathione stores

Generally, the conversion of nonlipidated soluble LC3 (LC3-I) to phosphatidylethanolamine-conjugated LC3 (LC3-II) serves as a hallmark of autophagy 21 , and immunoblot analysis revealed a dramatic increase in the ratio of LC3-II to LC3-I in response to glucose deprivation in MiaPaCa-2 and SW1990 cells (Fig